Science
Billions Poured Into Dementia Research Missed Something — The Identity of the 'Janitor Cells' Hiding in the Middle of the Brain
Alzheimer's research spent decades fixated on amyloid, but scientists have now discovered that tanycytes — cells lining the third ventricle — serve as critical janitors that flush tau protein into the bloodstream. If their deterioration accelerates dementia, the entire treatment paradigm may need to shift.